ORGANO PHOSPHORUS COMPOUNDS CHEMISTRY DEPARTMENT

The Department was founded by Academician A.V.Kirsanov on the basis of Pesticide Laboratory created in 1951. Since 1956 till 1978 the Department was headed by Prof. V.I.Shevchenko, since 1978 till 2009 Prof. O.M.Pinchuk guided the Department. Dr. O.M.Kostiuk was appointed as the head of the Department in 2009. The staff has 2 Doctors of science and 11 Candidates of science. The Department includes a Laboratory of Chemical Processes Under Pressure guided by Ph.D. O.O.Yurchenko.

The main scientific activity of the department – a theoretical and practical development of the chemistry of organophosphorus compounds. Key research activity is the synthesis and study of new types of elementoorganic compounds. The aim of the research is to create a basic methodology to obtain phosphorus-containing analogs of natural and bioactive compounds, the design of new types of phosphorus-containing ligands for metal-complex catalysis, reduction to practice in nanotechnology of organophosphorus compounds with useful properties.

One of the fundamental problems of chemical organophosphorus compounds is the development of preparative methods for the synthesis of compounds featuring a carbon-phosphorus bond. Among them, a special place takes functionalized phosphines and their derivatives, for which methods of synthesis are developed in the department. The department also carries out fundamental researches on the development of innovative methods for synthesis of acyclic and heterocyclic compounds bearing C-P and NP bonds. Applied researches of the department are associated with the use of organophosphorus compounds as biologically active agents, complexing agents, catalysts, reagents in organic and element-organic syntheses.

The main scientific and practical achievements of the Department. The department carried out fundamental research on the development of methods for creating carbon-phosphorus bonds,  eleborated original methods of electrophilic phosphorylation of electron-rich unsaturated, aromatic and heterocyclic compounds by phosphorus (III) halides, developed a general approach to phosphorus-containing fused heterocycles, hardly accessible λ⁵-phosphinines and λ⁵-azaphosphinines. New ferrocenylphosphines were synthesized and studied as ligands.

New types of ligands based on phosphorylated heterocycles including water-soluble ones were successfully used in palladium catalyzed asymmetric reactions. New classes of organo-phosphorus compounds were used as complexing agents for heavy metals, catalysts for organic synthesis and biologically active substances in agriculture. Systematic research in the field of synthesis and application of organophosphorus compounds, in particular development of promising direction creating nanoscale phosphorus-containing catalysts for cross-coupling reactions and asymmetric synthesis were carried out.

 

The department staff

• Kostiuk Alexander
• Pinchuk Alexander
• Chaikovskaya Alexandra
• Lavrova Olena
• Yurchenko Alexander
• Marchenko Anatoly
• Koidan Georgyi
• Merkulov Anatoly
• Nazarenko Konstantin
• Stepanenko Irina
• Yurchenko Sergey
• Lahtadyr Alexander
• Kovaleva Svetlana
• Hurieva Anastasiya
• Volokytin Alexander
• Shvydenko Tatiana
• Shtil Natalia
• Savateev Alexander
• Zadorozhnyy Alexander
• Lavrynovych Sergey

Publications

(1)      Marchenko, A.; Koidan, G.; Hurieva, A.; Savateev, A.; Rozhenko, A. B.; Sotiropoulos, J.-M.; Shishkina, S. V; Shishkin, O. V; Kostyuk, A. Eur. J. Inorg. Chem. 2014, n/a–n/a.

(2)      Marchenko, A.; Koidan, H.; Huryeva, A.; Smaliy, R.; Vlasenko, Y.; Gutov, O.; Kostyuk, A. Heteroat. Chem. 2014, 25, 1–9.

(3)      Shvidenko, T.; Nazarenko, K.; Shvidenko, K.; Kostyuk, A. Tetrahedron Lett. 2014, 55, 279–281.

(4)      Allouch, F.; Vologdin, N. V; Cattey, H.; Pirio, N.; Naoufal, D.; Kanj, A.; Smaliy, R. V; Savateev, A.; Marchenko, A.; Hurieva, A.; Koidan, H.; Kostyuk, A. N.; Hierso, J.-C. J. Organomet. Chem. 2013, 735, 38–46.

(5)      Kirilchuk, A. A.; Marchenko, A. P.; Koidan, H. G.; Zarudnitskii, E. V; Huryeva, A. N.; Yurchenko, A. A.; Kostyuk, A. N. Phosphorus, Sulfur Silicon Relat. Elem. 2013, 188, 254–255.

(6)      Marchenko, A. P.; Koidan, H. N.; Hurieva, A. N.; Gutov, O. V; Kostyuk, A. N.; Tubaro, C.; Lollo, S.; Lanza, A.; Nestola, F.; Biffis, A. Organometallics 2013, 32, 718–721.

(7)      Marchenko, A.; Koidan, G.; Hurieva, A.; Savateev, A.; Kostyuk, A. Tetrahedron Lett. 2013, 54, 5671–5673.

(8)      Smaliy, R. V; Chaykovskaya, A. A.; Shtil, N. A.; Savateev, A. S.; Kostyuk, A. N. Heteroat. Chem. 2013, 24, 146–151.

(9)      Marchenko, A. P.; Koidan, H. N.; Pervak, I. I.; Huryeva, A. N.; Zarudnitskii, E. V; Tolmachev, A. A.; Kostyuk, A. N. Tetrahedron Lett. 2012, 53, 494–496.

(10)    Marchenko, A. P.; Koidan, G. N.; Huryeva, A. N.; Merkulov, A. S.; Kostyuk, A. N. Heteroat. Chem. 2012, 23, 309–313.